April 2021

•Mediterranean Cruises•

Set sail in April 2021 on a Mediterranean cruise with all the major cruise lines.  More itineraries coming soon.  Call your local cruise specialists for availability and pricing... you could be enjoying a Mediterranean cruises for less!

April 2021 Mediterranean Cruises

Not looking for a April 2021 Mediterranean cruise, no problem, simply choose another month from the navigation and view many more Med cruises.

Oceania Cruises | Sirena, 1 April 2021
Aegean Encounter – 6 Nights
Athens, Mykonos, Santorini, Rhodes, Ephesus, Mitilini, Istanbul

P&O Cruises | Azura, 1 April 2021
Mediterranean – 7 Nights
Valletta, Dubrovnik, Hvar, Trieste, Split, Valletta

Silversea Cruises | Silver Moon, 1 April 2021
Barcelona to Athens (Piraeus) – 11 Nights
Barcelona, Monte Carlo, Livorno, Rome, Naples, Giardini Naxos, Valletta, Rhodes Island, Santorini, Athens

P&O Cruises | Azura, 1 April 2021
Mediterranean – 14 Nights
Valletta, Dubrovnik, Hvar, Trieste, Split, Valletta, Athens, Ephesus, Rhodes, Santorini, Valletta

MSC Cruises | MSC Virtuosa, 2 April 2021
Mediterranean – 7 Nights
Barcelona, Marseille, Genoa, Civitavecchia, Palermo, Valletta, Barcelona

Costa Cruises | Costa Smeralda, 2 April 2021
Mediterranean from Civitavecchia/Rome – 7 Nights
Civitavecchia/Rome, Savona, Marseilles, Barcelona, Palma, Palermo, Civitavecchia/Rome

Oceania Cruises | Riviera, 3 April 2021
Opulent Mediterranean – 9 Nights
Barcelona, Palamos, Provence, Monte Carlo, Saint-Tropez, Florence, Valletta, Messina, Naples, Rome

Costa Cruises | Costa Smeralda, 3 April 2021
Mediterranean from Savona – 7 Nights
Savona, Marseille, Barcelona, Palma De Mallorca, Palermo, Civitavecchia, Savona

Regent Seven Seas Cruises | Seven Seas Mariner, 3 April 2021
Dubai to Barcelona – 30 Nights
Dubai, Salalah, Aqaba, Luxor, Jerusalem, Limassol, Rhodes, Patmos, Mytilini, Istanbul, Bozcaada, Ephesus, Santorini, Amalfi/Positano, Rome, Tuscany, Monte Carlo, Provence, Barcelona

P&O Cruises | Ventura, 3 April 2020
Spain and Portugal – 14 Nights
Southampton, Lisbon, Cartagena, Valencia, Gibraltar, Cadiz, Porto, La Coruna, Southampton

MSC Cruises | MSC Virtuosa, 3 April 2021
Mediterranean – 7 Nights
Marseille, Genoa, Civitavecchia, Palermo, Valletta, Barcelona, Marseille

Celebrity Cruises | Celebrity Constellation, 3 April 2021
Dubai, Suez Canal & Greece – 15 Nights
Dubai, Muscat, Aqaba, Suez Canal, Rhodes, Ephesus, Athens

Costa Cruises | Costa Fortuna, 4 April 2021
Mediterranean from Savona – 7 Nights
Savona, Marseille, Barcelona, Valencia, Palermo, Naples, Savona

MSC Cruises | MSC Virtuosa, 4 April 2021
Mediterranean – 7 Nights
Genoa, Civitavecchia, Palermo, Valletta, Barcelona, Marseille, Genoa

Costa Cruises | Costa Fortuna, 5 April 2021
Mediterranean from Marseilles – 7 Nights
Marseille, Barcelona, Valencia, Palermo, Naples, Savona, Marseille

P&O Cruises | Aurora, 5 April 2021
Mediterranean – 19 Nights
Southampton, Vigo, Cartagena, Cagliari, Trapani, Salerno, Rome, Barcelona, Tarragona, Gibraltar, Lisbon, Southampton

MSC Cruises | MSC Virtuosa, 5 April 2021
Mediterranean – 7 Nights
Civitavecchia, Palermo, Valletta, Barcelona, Marseille, Genoa, Civitavecchia

MSC Cruises | MSC Virtuosa, 6 April 2021
Mediterranean – 7 Nights
Palermo, Valletta, Barcelona, Marseille, Genoa, Civitavecchia, Palermo

TUI Cruises | Marella Dream, 6 April 2021
Mediterranean Medley followed by Treasures of the Mediterranean – 14 Nights
Palma, Livorno, Savona, Toulon, Barcelona, Valencia, Palma, Palermo, Naples, Civitavecchia, Ajaccio, Palamos, Palma

Costa Cruises | Costa Fortuna, 6 April 2021
Mediterranean from Barcelona – 7 Nights
Barcelona, Valencia, Palermo, Naples, Savona, Marseille, Barcelona

TUI Cruises | Marella Dream, 6 April 2021
Mediterranean Medley – 7 Nights
Palma, Livorno, Savona, Toulon, Barcelona, Valencia, Palma

TUI Cruises | Marella Celebration, 7 April 2021
Ancient Affair followed by Aegean Titans – 14 Nights
Limassol, Alanya, Marmaris, Heraklion, Ashdod, Limassol, Souda, Piraeus, Mykonos Town, Kusadasi, Rhodes Town, Limassol

TUI Cruises | Marella Celebration, 7 April 2021
Ancient Affair – 7 Nights
Limassol, Alanya, Marmaris, Heraklion, Ashdod, Limassol

Regent Seven Seas Cruises | Seven Seas Splendor, 8 April 2021
Barcelona to Barcelona – 10 Nights
Barcelona, Arrecife, Santa Cruz de Tenerife, Santa Cruz de La Palma, Tangier, Cartagena, Valencia, Barcelona

Oceania Cruises | Sirena, 8 April 2021
Mediterranean Fusion – 9 Nights
Istanbul, Bozcaada, Ephesus, Heraklion, Naples, Rome, Florence, Monte Carlo, Provence, Barcelona

P&O Cruises | Azura, 8 April 2021
Mediterranean – 7 Nights
Valletta, Athens, Ephesus, Rhodes, Santorini, Valletta

Regent Seven Seas Cruises | Seven Seas Splendor, 8 April 2021
Barcelona to Monte Carlo – 17 Nights
Barcelona, Arrecife, Santa Cruz de Tenerife, Santa Cruz de La Palma, Tangier, Cartagena, Valencia, Barcelona, Palma de Mallorca, Ajaccio, Olbia/Porto Cervo, Sorrento/Capri, Rome, Tuscany, Monte Carlo

P&O Cruises | Azura, 8 April 2021
Mediterranean – 14 Nights
Valletta, Athens, Ephesus, Rhodes, Santorini, Valletta, Ajaccio, Livorno, Rome, Naples, Valletta

Fred. Olsen Cruises | Boudicca, 8 April 2021
Closer Spain & Cruising the Seine – 9 Nights
Dover, Honfleur, Santander, Aviles, La Coruna, Cruising River Seine, Rouen, Dover

P&O Cruises | Britannia, 9 April 2021
Western Europe – 7 Nights
Southampton, Gijon, La Coruna, Bilbao, Cherbourg, Southampton

MSC Cruises | MSC Virtuosa, 9 April 2021
Mediterranean – 7 Nights
Barcelona, Marseille, Genoa, Civitavecchia, Palermo, Valletta, Barcelona

MSC Cruises | MSC Virtuosa, 10 April 2021
Mediterranean – 7 Nights
Marseille, Genoa, Civitavecchia, Palermo, Valletta, Barcelona, Marseille

MSC Cruises | MSC Virtuosa, 11 April 2021
Mediterranean – 7 Nights
Genoa, Civitavecchia, Palermo, Valletta, Barcelona, Marseille, Genoa

NCL Cruises | Norwegian Getaway, 11 April 2021
Transatlantic from New York City – 17 Nights
New York, Royal Naval, Ponta Delgada, Lisbon, Seville, Granada, Cartagena, Palma, Barcelona, Cannes, Florence/Pisa, Rome

Costa Cruises | Costa Fortuna, 11 April 2021
Mediterranean from Savona – 7 Nights
Savona, Marseille, Barcelona, Valencia, Palermo, Naples, Savona

NCL Cruises | Norwegian Getaway, 11 April 2021
Transatlantic from New York City – Fly & Cruise – 17 Nights
New York, Royal Naval Dockyard, Ponta Delgada, Lisbon, Seville, Granada, Cartagena, Palma, Barcelona, Cannes, Florence/Pisa, Rome

Costa Cruises | Costa Fortuna, 12 April 2021
Mediterranean from Marseilles – 7 Nights
Marseille, Barcelona, Valencia, Palermo, Naples, Savona, Marseille

MSC Cruises | MSC Virtuosa, 12 April 2021
Mediterranean – 7 Nights
Civitavecchia, Palermo, Valletta, Barcelona, Marseille, Genoa, Civitavecchia

NCL Cruises | Norwegian Dawn, 12 April 2021
Italy and Greek Isles from Rome (Civitavecchia) – 10 Nights
Rome, Monte Carlo, Florence/Pisa, Naples, Santorini, Athens, Mykonos, Argostoli, Kotor, Dubrovnik, Venice

NCL Cruises | Norwegian Dawn, 12 April 2021
Italy and Greek Isles from Rome (Civitavecchia) – Fly & Cruise – 10 Nights
Rome, Monte Carlo, Florence/Pisa, Naples, Santorini, Athens, Mykonos, Argostoli, Kotor, Dubrovnik, Venice

Costa Cruises | Costa Fortuna, 13 April 2021
Mediterranean from Barcelona – 7 Nights
Barcelona, Valencia, Palermo, Naples, Savona, Marseille, Barcelona

MSC Cruises | MSC Virtuosa, 13 April 2021
Mediterranean – 7 Nights
Palermo, Valletta, Barcelona, Marseille, Genoa, Civitavecchia, Palermo

Silversea Cruises | Silver Moon, 13 April 2021
Athens (Piraeus) to Venice – 8 Nights
Athens, Kusadasi, Rhodes, Island, Corfu, Kotor, Split, Trieste, Venice

Oceania Cruises | Riviera, 13 April 2021
Italy & The Adriatic – 9 Nights
Rome, Amalfi, Catania, Valletta, Corfu, Kotor, Split, Ravenna, Koper, Venice

TUI Cruises | Marella Dream, 13 April 2021
Treasures of the Mediterranean followed by Mediterranean Medley – 14 Nights
Palma, Palermo, Naples, Civitavecchia, Ajaccio, Palamos, Palma, Livorno, Savona, Toulon, Barcelona, Valencia, Palma

TUI Cruises | Marella Dream, 13 April 2021
Treasures of the Mediterranean – 7 Nights
Palma, Palermo, Naples, Civitavecchia, Ajaccio, Palamos, Palma

TUI Cruises | Marella Celebration, 14 April 2021
Aegean Titans followed by Ancient Affair – 14 Nights
Limassol, Souda, Piraeus, Mykonos Town, Kusadasi, Rhodes Town, Limassol, Alanya, Marmaris, Heraklion, Ashdod, Limassol

P&O Cruises | Azura, 15 April 2021
Mediterranean – 7 Nights
Valletta, Ajaccio, Livorno, Rome, Naples, Valletta

TUI Cruises, Marella Celebration, 14 April 2021
Aegean Titans – 7 Nights
Limassol, Souda, Piraeus, Mykonos Town, Kusadasi, Rhodes Town, Limassol

P&O Cruises | Azura, 15 April 2021
Mediterranean – 14 Nights
Valletta, Ajaccio, Livorno, Rome, Naples, Valletta, Kotor, Split, Trieste, Zadar, Valletta

NCL Cruises | Norwegian Escape, 16 April 2021
Transatlantic from New York – 14 Nights
New York, Royal Naval Dockyard, Ponta Delgada, Lisbon, Vigo, Brussels/Bruges, Paris, Southampton

Fred. Olsen Cruises | Braemar, 16 April 2021
Greek Islands & Corinth Canal – 25 Nights
Southampton, Malaga, Valletta, Agios Nikolaos, Rhodes, Ermoupoli, Cruising Corinth Canal, Patras, Katakolon, Cruise Strait of Messina, Cruising by Stromboli, Trapani, Ibiza, Cartagena, Lisbon, Southampton

MSC Cruises | MSC Virtuosa, 16 April 2021
Mediterranean – 7 Nights
Barcelona, Marseille, Genoa, Civitavecchia, Palermo, Valletta, Barcelona

Princess Cruises | Enchanted Princess, 17 April 2021
Western Mediterranean & Aegean Medley – 13 Nights
Barcelona, Gibraltar, Marseille, Genoa, Florence/Pisa, Rome, Naples, Crete, Kusadasi, Istanbul, Mykonos, Athens

Princess Cruises | Enchanted Princess, 17 April 2021
Mediterranean – 6 Nights
Barcelona, Gibraltar, Marseille, Genoa, Florence/Pisa, Rome

MSC Cruises | MSC Virtuosa, 17 April 2021
Mediterranean – 7 Nights
Marseille, Genoa, Civitavecchia, Palermo, Valletta, Barcelona, Marseille

Princess Cruises | Enchanted Princess, 17 April 2021
Mediterranean Collection (from Barcelona) – 20 Nights
Barcelona, Gibraltar, Genoa, Florence/Pisa, Rome, Naples, Crete, Kusadasi, Istanbul, Mykonos, Athens, Santorini, Kotor, Sicily, Naples, Barcelona

Regent Seven Seas Cruises | Seven Seas Splendor, 18 April 2021
Barcelona, Palma de Mallorca, Ajaccio, Olbia/Porto Cervo, Sorrento/Capri, Rome, Tuscany, Monte Carlo

Costa Cruises | Costa Fortuna, 18 April 2021
Mediterranean from Savona – 7 Nights
Savona, Marseille, Barcelona, Valencia, Palermo, Naples, Savona

Silversea Cruises | Silver Spirit, 18 April 2021
Athens (Piraeus) to Athens (Piraeus) – 6 Nights
Athens, Mykonos Island, Kusadasi, Rhodes Island, Agios, Nikolaos, Santorini, Nafplion, Athens

Oceania Cruises | Sirena, 18 April 2021
Marquee Mediterranean – 11 Nights
Barcelona, Valencia, Mahon, Cagliari, Valletta, Syracuse, Sorrento, Rome, Florence, Monte Carlo, Provence

MSC Cruises | MSC Virtuosa, 18 April 2021
Mediterranean – 7 Nights
Genoa, Civitavecchia, Palermo, Valletta, Barcelona, Marseille, Genoa

Costa Cruises | Costa Fortuna, 19 April 2021
Mediterranean from Marseilles – 7 Nights
Marseille, Barcelona, Valencia, Palermo, Naples, Savona, Marseille

Costa Cruises | Costa Fortuna, 20 April 2021
Mediterranean from Barcelona – 7 Nights
Barcelona, Valencia, Palermo, Naples, Savona, Marseille, Barcelona

Princess Cruises | Grand Princess, 20 April 2021
European Explorer – 9 Nights
Rome, Florence/Pisa, Monte Carlo, Barcelona, Gibraltar, Lisbon, Paris/Normandy, London

TUI Cruises | Marella Dream, 20 April 2021
Mediterranean Medley – 7 Nights
Palma, Livorno, Savona, Toulon, Barcelona, Valencia, Palma

TUI Cruises | Marella Celebration, 21 April 2021
Ancient Affair – 7 Nights
Limassol, Alanya, Marmaris, Heraklion, Ashdod, Limassol

P&O Cruises | Azura, 22 April 2021
Mediterranean – 7 Nights
Valletta, Kotor, Split, Trieste, Zadar, Valletta

P&O Cruises | Azura, 22 April 2021
Mediterranean – 14 Nights
Valletta, Kotor, Split, Trieste, Zadar, Valletta, Rome, Livorno, Monte Carlo, Ajaccio, Valletta

Silversea Cruises | Silver Moon, 22 April 2021
Venice to Athens (Piraeus) – 11 Nights
Venice, Split, Dubrovnik, Corfu, Argostoli, Souda Bay, Rhodes Islands, Istanbul, Dikili, Kusadasi, Athens

Oceania Cruises | Riviera, 23 April 2021
Ancient Adventures – 11 Nights
Venice, Koper, Dubrovnik, Kotor, Corfu, Taormina, Amalfi, Rome, Florence, Monte Carlo, Saint-Tropez, Provence, Barcelona

Oceania Cruises | Marina, 23 April 2021
Coastlines & Colonnades – 6 Nights
Rome, Naples, Messina, Argostoli, Gythion, Santorini, Ephesus, Athens

Regent Seven Seas Cruises, Seven Seas Mariner, 23 April 2021
Istanbul to Barcelona – 10 Nights
Istanbul, Bozcaada, Ephesus, Santorini, Amalfi/Positano, Rome, Tuscany, Monte Carlo, Provence, Barcelona

MSC Cruises | MSC Virtuosa, 23 April 2021
Mediterranean – 3 Nights
Barcelona, Marseille, Genoa, Barcelona

NCL Cruises | Norwegian Dawn, 23 April 2021
Italy and Greek Isles from Venice – 8 Nights
Venice, Kotor, Corfu, Santorini, Athens, Mykonos, Argostoli, Dubrovnik, Split, Venice

NCL Cruises | Norwegian Dawn, 23 April 2021
Italy and Greek Isles from Venice – Fly & Cruise – 8 Nights
Venice, Kotor, Corfu, Santorini, Athens, Mykonos, Argostoli, Dubrovnik, Split, Venice

MSC Cruises | MSC Virtuosa, 24 April 2021
Mediterranean – 3 Nights
Marseille, Genoa, Barcelona, Marseille

Princess Cruises | Enchanted Princess, 24 April 2021
Adriatic & Aegean Medley – 13 Nights
Rome, Naples, Crete, Kusadasi, Istanbul, Mykonos, Athens, Santorini, Kotor, Sicily, Naples, Barcelona

Princess Cruises | Enchanted Princess, 24 April 2021
Mediterranean & Aegean – 6 Nights
Rome, Naples, Crete, Kusadasi, Istanbul, Mykonos, Athens

Princess Cruises | Enchanted Princess, 24 April 2021
Mediterranean Collection (from Rome) – 20 Nights
Rome, Naples, Crete, Kusadasi, Istanbul, Mykonos, Athens, Santorini, Kotor, Sicily, Naples, Barcelona, Gibraltar, Marseille, Genoa, Florence/Pisa, Rome

P&O Cruises | Aurora, 24 April 2021
Western Europe – 7 Nights
Southampton, Vigo, Lisbon, Porto, St. Peter Port, Southampton

Regent Seven Seas Cruises | Seven Seas Splendor, 25 April 2021
Monte Carlo to London (Southampton) – 15 Nights
Monte Carlo, Provence, Barcelona, Malaga, Casablanca, Seville, Lisbon, Oporto, Ferrol, Bilbao, Bordeaux, Saint-Malo, Southampton

Costa Cruises | Costa Fortuna, 25 April 2021
Mediterranean from Savona – 4 Nights
Savona, Barcelona, Marseille, Savona

Silversea Cruises | Silver Spirit, 25 April 2021
Athens (Piraeus) to Rome (Civitavecchia) – 9 Nights
Athens, Mykonos Island, Kusadasi, Rhodes Island, Santorini, Souda Bay, Giardini Naxos, Sorrento, Rome

NCL Cruises | Norwegian Epic, 25 April 2021
Western Mediterranean from Barcelona – 2 Nights
Barcelona, Naples, Rome

MSC Cruises | MSC Virtuosa, 25 April 2021
Mediterranean – 3 Nights
Genoa, Barcelona, Marseille, Genoa

NCL Cruises | Norwegian Epic, 25 April 2021
Western Mediterranean from Barcelona – 6 Nights
Barcelona, Naples, Rome, Florence/Pisa, Cannes, Palma, Barcelona

P&O Cruises | Britannia, 25 April 2021
Spain and Portugal – 13 Nights
Southampton, La Coruna, Cadiz, Malaga, Valencia, Cartagena, Lisbon, Southampton

Regent Seven Seas Cruises | Seven Seas Voyager, 26 April 2021
Barcelona to Athens (Piraeus) – 9 Nights
Barcelona, Provence, Monte Carlo, Rome, Sorrento/Capri, Taormina, Santorini, Ephesus, Athens

Costa Cruises | Costa Fortuna, 26 April 2021
Mediterranean from Marseilles – 4 Nights
Marseille, Barcelona, Savona, Marseille

Costa Cruises | Costa Fortuna, 27 April 2021
Mediterranean from Barcelona – 4 Nights
Barcelona, Savona, Marseille, Barcelona

NCL Cruises | Norwegian Epic, 28 April 2021
Western Mediterranean from Rome (Civitavecchia) – 6 Nights
Rome, Florence/Pisa, Cannes, Palma, Barcelona, Naples, Rome

Silversea Cruises | Silver Shadow, 28 April 2021
Lisbon to Barcelona – 11 Nights
Lisbon, Funchal, San Sebastian, Canary Islands, Arrecife, Casablanca, Cadiz, Palma De Mallorca

Costa Cruises | Costa Fortuna, 29 April 2021
Mediterranean from Savona – 3 Nights
Savona, Marseille, Barcelona, Savona

NCL Cruises | Norwegian Getaway, 29 April 2021
Greek Isles & Italy from Rome (Civitavecchia) – 10 Nights
Rome, Kotor, Dubrovnik, Corfu, Santorini, Mykonos, Athens, Naples, Florence/Pisa, Rome

P&O Cruises | Azura, 29 April 2021
Mediterranean – 7 Nights
Valletta, Rome, Livorno, Monte Carlo, Ajaccio, Valletta

P&O Cruises | Azura, 29 April 2021
Mediterranean – 14 Nights
Valletta, Rome, Livorno, Monte Carlo, Ajaccio, Valletta, Mykonos, Souda Bay, Athens, Santorini, Valletta

MSC Cruises | MSC Magnifica, 29 April 2021
Mediterranean – 5 Nights
Genoa, Civitavecchia, Barcelona, Marseille, Genoa

Costa Cruises | Costa Fortuna, 30 April 2021
Mediterranean from Marseilles – 3 Nights
Marseille, Barcelona, Savona, Marseille

Oceania Cruises | Sirena, 30 April 2021
European Vintages – 11 Nights
Barcelona, Alicante, Granada, Seville, Lisbon, Oporto, San Sebastian, Bordeaux, Lorient, St. Peter Port, London

Oceania Cruises | Marina, 30 April 2021
Medieval Masterpiece – 23 Nights
Athens, Mykonos, Ephesus, Patmos, Marmaris, Chania, Katakolon, Corfu, Dubrovnik, Ravenna, Rijeka, Venice, Split, Kotor, Syracuse, Sorrento, Rome, Florence, Monte Carlo, Provence, Palamos, Palma de Mallorca, Barcelona

Oceania Cruises | Marina, 30 April 2021
Aegean Glories – 11 Nights
Athens, Mykonos, Ephesus, Patmos, Marmaris, Chania, Katakolon, Corfu, Dubrovnik, Ravenna, Rijeka, Venice